Predicted line-ups:
Mikel Arteta will be without defenders Gabriel, Ben White and Cristhian Mosquera, as well as Kai Havertz, due to injury.
Brighton will be missing Adam Webster, Solly March and Stefanos Tzimas due to injury, whilst Carlos Baleba is on Africa Cup of Nations duty.
Arsenal: Raya, Timber, Saliba, Hincapie, Calafiori, Zubimendi, Odegaard, Rice, Trossard, Saka, Gyokeres
Brighton & Hove Albion: Verbruggen, Wieffer, van Hecke, Dunk, De Cuyper, Ayari, Gomez, Minteh, Gruda, Kadioglu, Rutter
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